In Camelford, while swinging his van throughout a slim roadway to make a u-turn, a vehicle driver delays the automobile that does not restart. Hart Read is driving his motorbike with his girlfriend Rose and he drives off the road to avoid the accident. Hart suffers minor injuries while Rosie is injured and burned by the fires when the motorcycle blows up. The ambulance from the close-by Keloid Facility for Plastic Surgery brings the couple as well as Rose, who remains in coma, is sent to an emergency situation surgery as well as to a speculative plastic-surgery method by Dr. Dan Keloid to get her skin in the chest and abdominal area. Hart is discharged but Rose remains in coma in the critical care unit (ICU) to recoup. Unexpectedly, Rose stirs up from her coma one month later and also screams. A nurse aids her but is wounded by her and then he could not remember exactly what has taken place. He is sent to a hospital in Montreal while Rose recognizes that she has to feed with blood. However her sufferers come to be zombie-like animals. Rose flees from the facility to Montreal to fulfill her buddy Mindy Kent spreading her infection in the huge city. Meanwhile Hart is seeking for her.